An eight-member California blood-center consortium asked for help designing and developing an information tracking and management system for blood banking. The result is the SafeTrace donor-management information system. This system has comprehensive donor-recruitment capabilities, and can manage fixed site and mobile donor collection. It maintains real-time, historical donor demographic and deferral data. Its Oracle database is compatible with standard third-party database tools, interfaces with automated testing equipment, and supports current and emerging regulatory guidelines. Look to SafeTrace for donor management, final transfusion/product, laboratory, inventory/distribution, and billing requirements.